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TAGMe

He aha ka TAGMe

Kūʻokoʻa ka honua: Tumor Aligned General Methylated Epiprobe (TAGMe)

I ka hōʻoia ʻana ma mua o 3000 mau lāʻau lapaʻau, ʻoi aku ka kiʻekiʻe o ka pae methylation o TAGMe i loko o nā ʻiʻo ʻōpū ma mua o nā kiko maʻamau.No laila, hiki ke hoʻohana ʻia ʻo TAGMe ma ke ʻano he hōʻailona pan-cancer i ka ʻike ʻana i nā maʻi maʻi like ʻole.

He aha ka TAGMeHe aha ka TAGMe (1)

ʻO nā genes pili i ka histone i hypermethylated i ka maʻi kanesa a hiki i ka hypermethylated HIST1H4F ke lilo i mea biomarker pan-cancer.

————Ka Imi Kano,IF:12.7

Dehana hana

Ma ke ʻano he hōʻailona pan-cancer, loaʻa iā TAGMe ka kikoʻī kiʻekiʻe a me ka naʻau i ka hōʻoia hōʻoia hōʻailona hōʻoia, nona ka waiwai kuhikuhi koʻikoʻi no ka maʻi maʻi o nā maʻi maʻi.

He aha ka TAGMeHe aha ka TAGMe (2)

Paʻa ʻo TAGMe i nā ʻano ʻokoʻa ʻokoʻa inā ʻoi aku ka kikoʻī ma mua o 95%,