ʻO ka hopena no ka maʻi maʻi endometrial, e hoʻopau ana i ka maʻi kanesa ma ke kahua o nā lesion precancerous.ʻO ka maʻi maʻi endometrial kekahi o nā maʻi maʻi maʻi nui ʻekolu i ka gynecology.
ʻO ka maʻi ʻaʻai endometrial kekahi o nā maʻi maʻi maʻamau maʻamau i ka ʻōnaehana hānau wahine, ka lua ma waena o nā maʻi maʻi ʻōnaehana hānau wahine ma Kina, a ʻoi aku ka nui o nā wahine kūlanakauhale.Wahi a nā helu helu mai ka International Agency for Research on Cancer of the World Health Organization, aia ma kahi o 420,000 mau hihia hou o ka maʻi maʻi endometrial ma ka honua holoʻokoʻa i 2020, me kahi o 100,000 mau make.
ʻO kēia mau hihia, ma kahi o 82,000 mau hihia hou o ka maʻi maʻi endometrial i hōʻike ʻia ma Kina, me 16,000 mau make.Ua manaʻo ʻia ma ka makahiki 2035, aia he 93,000 mau hihia hou o ka maʻi maʻi endometrial ma Kina.
He kiʻekiʻe loa ka lāʻau lapaʻau no ka maʻi maʻi endometrial mua, me ka 5 makahiki ola ola a hiki i 95%.Eia nō naʻe, ʻo ka helu ola 5 makahiki no ka pae IV endometrial cancer he 19% wale nō.
ʻOi aku ka maʻamau o ka maʻi maʻi endometrial i nā wahine postmenopausal a me perimenopausal, me ka awelika o ka makahiki hoʻomaka ma kahi o 55 mau makahiki.Eia nō naʻe, i kēia mau makahiki i hala iho nei, ua piʻi ka maʻi maʻi maʻi endometrial ma waena o nā wahine he 40 a ma lalo.
I kēia manawa ʻaʻohe ala kānana kūpono no ka maʻi maʻi endometrial
No nā wāhine hānau keiki, hiki i ka nānā mua ʻana a me ka mālama ʻana i ka maʻi maʻi endometrial i ka manawa ke hoʻonui i ka mālama ʻana i ka momona a hāʻawi i kahi manawa no ke ola lōʻihi.
Eia nō naʻe, i kēia manawa ʻaʻohe ʻano hoʻokolohua maʻalahi a pololei ʻole no ka maʻi maʻi endometrial i ka hana lapaʻau.ʻO nā hōʻailona e like me ke kahe ʻana o ka vaginal maʻamau a me ka hoʻokuʻu ʻana o ka vaginal i ka wā mua e maʻalahi ke nānā ʻia, e hopena i kahi manawa nalo no ka ʻike mua.
ʻO ka nānā mua ʻana me ka hoʻohana ʻana i ke kiʻi ultrasound a me nā hoʻokolohua gynecological maʻamau he haʻahaʻa ka naʻau.
ʻO ka hoʻohana ʻana i ka hysteroscopy a me ka biopsy pathological he invasive, me ka anesthesia kiʻekiʻe a me ke kumukūʻai, a hiki ke hopena i ke koko, ka maʻi, a me ka perforation o ka ʻōpū, e alakaʻi ana i kahi kiʻekiʻe o ka maʻi i hala ʻole, a ʻaʻole hoʻohana ʻia ma ke ʻano he ʻano nānā maʻamau.
Hiki ke hōʻoluʻolu ʻia ke koko, ka maʻi, a me ka puka ʻana o ka ʻōpū i ka endometrial biopsy, e alakaʻi ana i kahi kiʻekiʻe o ka maʻi i hala.
TAGMe DNA Methylation Detection Kits (qPCR) no ka maʻi maʻi maʻi endometrialHoʻolaha i ka Era o Endometrial Cancer Diagnosis and Treatment 2.0
TAGMe DNA Methylation Detection Kits (qPCR) no ka maʻi maʻi maʻi endometrialhiki ke hoʻokō maikaʻi i nā hemahema o nā ʻano kānana maʻamau no ka maʻi maʻi endometrial, e hōʻemi nui i ka helu o ka maʻi i hala ʻole a kōkua i nā maʻi e ʻike i nā hōʻailona maʻi maʻi i ka manawa kūpono.
ʻO ka hoʻāʻo ʻelua makapō ʻo ia ka "standard gula" no ka hōʻoia ʻenehana a me ka maʻamau lapaʻau i mālama mau ʻia e Epiprobe!
Ua hōʻike ʻia nā hopena o ka hoʻāʻo ʻelua makapō no nā laʻana o ka cervical scrape, ʻo ka AUC he 0.86, kikoʻī ʻo 82.81%, a ʻo 80.65% ka naʻau;no nā laʻana o ka pulupulu ʻōpū, ʻo ka AUC he 0.83, ka kikoʻī he 95.31%, a ʻo ka sensitivity he 61.29%.
No nā huahana screening early cancer, ʻo ka pahuhopu nui ka nānā ʻana i nā poʻe pilikia ma mua o ka hana ʻana i kahi maʻi maʻi.
No nā huahana kānana mua ʻana i ka maʻi kanesa, e noʻonoʻo ana ʻo ke kumu o ka hoʻohana ʻana o ka mea hoʻohana ʻo ia ka hoʻopau ʻana i ka pilikia o ka maʻi a me ka pale ʻana i nā maʻi i hala ʻole e like me ka hiki, ʻo ia ka ʻoiaʻiʻo loa i ka poʻe i hoʻāʻo ʻia.
Ka waiwai wanana ino oTAGMe DNA Methylation Detection Kits (qPCR) no ka maʻi maʻi maʻi endometrialʻo 99.4%, ʻo ia hoʻi i ka heluna kanaka i loaʻa nā hopena maikaʻi ʻole, 99.4% o nā hopena maikaʻi ʻole he mau ʻoiaʻiʻo.He mea koʻikoʻi ka hiki ke pale aku i nā maʻi i hala, a ʻo ka hapa nui o nā mea hoʻohana maikaʻi ʻole hiki ke hoʻomaha i ka hōʻoia ʻaʻole pono lākou e hoʻopaʻa i ka invasive screening me nā helu kiʻekiʻe i hala.ʻO kēia ka pale nui loa no nā mea hoʻohana.
ʻO ka loiloi ponoʻī o nā kumu pilikia no ka maʻi maʻi endometrial.
Me ka hoʻomaikaʻi ʻana o nā kūlana ola, ke piʻi nei ka nui o ka maʻi maʻi endometrial ma Kina i kēlā me kēia makahiki, a aia ke ʻano i nā maʻi ʻōpio.
No laila, he aha ke ʻano o ka poʻe e hoʻomohala i ka maʻi maʻi endometrial?
ʻO ka mea maʻamau, ʻo ka poʻe e ulu ana i ka maʻi maʻi endometrial e loaʻa i nā ʻano ʻeono:
- E ʻeha mai ka metabolic syndrome: he maʻi i hōʻike ʻia e ka momona, ʻoi aku ka momona o ka ʻōpū, a me ke kō koko kiʻekiʻe, nā lipid koko abnormal, ke koko kiʻekiʻe, a me nā mea ʻē aʻe, e hoʻopilikia nui i ke olakino o ke kino;
- ʻO ka hoʻoulu ʻana o ka estrogen hoʻokahi lōʻihi: ʻike lōʻihi i ka hoʻoulu ʻana o ka estrogen hoʻokahi me ka ʻole o ka progesterone e pale ai i ka endometrium;
- ʻO ka menarche mua a me ka menopause hope: ʻo ia ke ʻano o ka piʻi ʻana o ka nui o nā kaʻina menstrual, no laila e ʻike ʻia ka endometrium i ka hoʻoulu ʻana o ka estrogen no kahi manawa lōʻihi;
- ʻAʻole hānau i nā keiki: i ka wā hāpai, kiʻekiʻe ke kiʻekiʻe o ka progesterone i ke kino, hiki ke pale i ka endometrium;
- Nā kumu genetic: ʻo ka mea maʻamau ʻo Lynch syndrome.Inā loaʻa nā maʻi ʻōpio o ka maʻi ʻaʻai kala, ka maʻi ʻōpū, a i ʻole nā ʻohana wahine me ka maʻi maʻi ovarian, ka maʻi maʻi endometrial, a me nā mea ʻē aʻe i waena o nā ʻohana pili, pono e hoʻomaopopo ʻia a hiki ke hana ʻia ka ʻōlelo aʻoaʻo genetic a me ka loiloi;
- ʻO nā ʻano nohona maikaʻi ʻole: e like me ka puhi ʻana, nele i ka hoʻomaʻamaʻa, a me ka makemake i nā meaʻai kiʻekiʻe-calorie a me nā momona momona e like me ka ʻuala, french fries, ka waiū kī, nā meaʻai palai, nā keke kokoleka, a me nā mea ʻē aʻe, no laila pono e hoʻoikaika kino. hou ma hope o ka ʻai ʻana iā lākou.
Hiki iā ʻoe ke hoʻohālikelike iā ʻoe iho me nā hiʻohiʻona 6 ma luna aʻe e hiki ke hoʻomohala i ka maʻi maʻi endometrial, a e hoʻāʻo e hoʻoponopono iā lākou e like me ka hiki ke pale aku mai ke kumu.
Ka manawa hoʻouna: Mei-09-2023